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Anthony W. Wren PDF Print E-mail

Assistant Professor

Biomaterials

 

Educational Background

B.Sc. Science - Biology, Exp. Physics, Math. Physics, Mathematics, National University of         Ireland, Maynooth, Ireland, 2003

M.Sc. Biomedical Engineering - Diagnostic Medical Devices, University of Limerick, Ireland,

            2005
Ph.D. Biomedical Materials - Bioactive Bone Cements, University of Limerick, Ireland, 2008

Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Phone: (607)871-2183

Location: Binns Merrill Hall 217

Website: http://cact.alfred.edu

 

Current and Recent Projects

 Dextran hydrogels as carriers for bioactive glasses. delivery of Gallium containing glasses for anti-tumor effects.

The effect of thermal treatment on the rheological and mechanical properties and bioactivity of Ti-glass polyalkenoate cemnts.

Sr-doped hydroxyapatite modified with bioactive glass, properties and bioactive effects.

The effect of alternating Na and Sr concentration on the structure of glass-ceramic scaffolds.

 

Research Overview

 

My primary research interests include designing and characterizing novel glasses for use as medical devices. Principal analytical techniques for glass design include X-ray Diffraction (XRD), X-ray Photoelectron Spectroscopy (XPS) and Raman Spectroscopy. Further interests include quantifying ion release from bioactive glasses/materials and their effect on common skin microflorasuch as bacteria (E. coli, S. epidermidis, S. aureus, P. aeruginosa) and yeast (candida albicans) responsible for infection. My research interests also include cytotoxicity testing of biomaterials on mammalian (Mouse L929 Fibroblasts) cells, with the intention to commence testing on both bone and cancer cell lines in the near future. My current research projects include:

 

• Fabrication of Glass/Ceramic Cell Scaffolds for increased bioactivity.

 

• Glass Coatings to increase the antimicrobial response and their subsequent diffusion through soluble and stable Hydrogels/Gels for applications in wound healing.

 

• Bone Cements based on Glass Polyalkenoate Cement chemistry for load bearing applications.

 

• Anti-cancerous Bone Cements and Degradable Bioactive Glasses.

 

Selected Publications

 

Fabrication of CaO-NaO-SiO2/TiO2 scaffolds for surgical applications.A.W. Wren, A. Coughlan, K.E. Smale, S.T. Misture, B.P. Mahon, O.M. Clarkin, M.R. Towler. J. Mat. Sci: Mater. Med. DOI: 10.1007/s10856-012-4746-8 2012.

 

Gallium containing glass polyalkenoate anti-cancerous bone cements:glass characterization and physical properties. J. Mat. Sci: Mater. Med. 23 : 8 1823-1833 2012.

 

Silver coated bioactive glass particles for wound healing applications. A.W. Wren, A. Coughlan, P. Hassanzadeh, M.R. Towler. J. Mat. Sci: Mater. Med. 23: 5 1331-1341 2012.

 

The Structural Role of Titanium in Ca-Sr-Zn-Si/Ti Glasses for Medical Applications. A.W. Wren, A. Kidari, F.R. Laffir, M.R. Towler. J Non-Crys. Solids. 357: 3 1021-1026 2011.

 

The Bioactivity and Ion Release of Titanium-Containing Glass Polyalkenoate Cements for Medical Applications. A.W. Wren, N.M. Cummins, F.R. Laffir, S.P. Hudson, M.R. Towler. J. Mat. Sci: Mater. Med. 22: 19-28 2011.

 

Solgel derived silver incorporated titania thin films on glass: bactericidal and photocatalytic activity. B.A. Akgun, A.W. Wren, C. Durucan, M.R. Towler, N.P. Mellott, J. Sol-Gel Sci. 59: 2 228-238 2011.

 

 

 

Industry Advisors


As a complement, the Center for Advanced Ceramic Technology (CACT) is building a "Team" of Industry Advisors from a broad spectrum of industries experienced in a wide range of industries such as Energy, Healthcare, and Environment.

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NYSTAR


The Center for Advanced Ceramic Technology is sponsored by the New York State Foundation for Science, Technology and Innovation.

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Short Courses


For those interested in increasing their expertise in the field of ceramics and glasses, or those just being introduced, Short Courses are a good option. Designed for professionals in the ceramics and glass industry, these intensive courses offer a chance to update knowledge of the field in a short period of time.  Courses range from detailed, in-depth examinations of very specific topics to broader introductory classes.

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